CLINICAL RESEARCH DATA.

Aggregate clinical trial data and in vivo studies.

Clinical Data Aggregation

Our database compiles 400+ peer-reviewed trials focusing on strain-specific efficacy. Generalized claims about "Lactobacillus" are biologically meaningless without strain designation (e.g., L. rhamnosus GG ATCC 53103). The variance in survival against gastric acid (pH 2.0) can differ by 4 logs between strains of the same species (Smith & Jones, 2021).

Plot showing gastric survival variance
Fig 2: 4-log survival variance among L. rhamnosus sub-strains at pH 2.0.

Strain Efficacy Summary

StrainPrimary IndicationNNT (Number Needed to Treat)
L. plantarum 299vIBS Abdominal Pain4
B. infantis 35624Systemic Inflammation7

Tool: Strain Specificity Matcher

Common Mistakes in Research Interpretation

  • Extrapolating in vitro data directly to in vivo efficacy without accounting for gut health environment variables.
  • Ignoring the vehicle of administration (capsule vs dairy matrix) which drastically impacts live cell viability.

FAQ Section

What is NNT in these tables?
Number Needed to Treat (NNT) is the epidemiological measure indicating how many patients need to be treated with the product for one to see a benefit compared to placebo. A lower number is better.
Do you sponsor clinical trials?
Bioticine operates as an independent analysis platform; we aggregate and review external trials to ensure unbiased scientific principles are upheld.